Even at this early stage of the season, Borussia Dortmund have already made every game a must-win if they are to apply any pressure on Bayern Munich in the Bundesliga title race.
Heading into this Saturday's clash with bottom club Hamburger SV, Dortmund currently sit 12th in the table with just seven points from six games.
Klopp will desperate to a similar display in the league after going three Bundesliga games without a win, and he could be tempted to limit the changes he makes to his side.
However, there is likely to be a place in the team for Adrian Ramos, who impressed his manager with a brace coming off the bench in Belgium.
Dortmund will be meeting a side whose needs are similarly desperate to their own, with the visitors still searching for their first win of the new season.
Borussia Dortmund: LWWLDL
Hamburger SV: DLLDLL
Possible starting lineups
Borussia Dortmund: Weidenfeller, Piszczek, Subotic, Sokratis, Schmelzer, Bender, Kehl, Groskreutz, Ramos Immobile, Aubameyang
Hamburger SV: Drobny, Cleber, Ostrzolek, Djourou, Westermann, Behrami, Stieber, Arslan, Jiracek, Holtby, Lasogga
Sports Mole says: 3-0