Benfica currently occupy third spot in the table with four points and have enjoyed an unbeaten start to their domestic season. Furthermore, they have won six of their last seven games in all competitions.
A famous win over Barcelona in their last group match has left Celtic needing just three points to qualify for the knockout stages, but they have never beaten Benfica in Lisbon.
Meanwhile, Neil Lennon's side are currently top of their domestic league and enter the match having not lost any of their last five matches.
Benfica will have Luisao available after suspension, while Eduardo Salvio could also be handed a spot in attack. Celtic are still without top scorer Gary Hooper, but Kris Commons and Georgios Samaras are both expected to be available.
Benfica: Artur; Pereira, Jardel, Garay, Almeida; Matic, Gaitan, Perez; Lima, Cardozo, Rodrigo
Celtic: Forster; Matthews, Ambrose, Wilson, Mulgrew; Brown, Wanyama; Commons, Ledley, Lassad; Samaras
Sports Mole says: 2-1