This encounter is set to be a fascinating affair with both sides close to the summit of the form table, each with four wins in their last six games.
It is fair to say the hosts have exceeded expectations this season. They currently sit in ninth place, having picked up 34 points from their 23 league fixtures so far.
As a result, they are only three points away from a playoff spot, something that would have looked unlikely at the start of the season having narrowly avoided relegation last time out.
The Tykes' fruitful form can in part be put down to their strong performances at home, and should they win on Saturday, it will be the first time they have won four consecutive home games since 2007 - truly a sign that this side are going in the right direction.
Steve Cooper will be delighted with his team's form of late and will feel his side are worthy of their position in the league, where they trail leaders Norwich by four points.
As well as having players that can unlock some of the division's best defences, such as Andre Ayew and Jamal Lowe, the Swans actually have the best defence in the league, having conceded only 13 goals so far this season.
In fact, that is the fewest conceded by a team after 23 games since 2015-16, when Middlesbrough had conceded 12 at this stage.
Following the matchup with Barnsley, Cooper's men travel to Blackburn Rovers and Rotherham United, before then locking horns with the Canaries in what will be a much-anticipated affair.
Barnsley Championship form: WWLWWL
Barnsley form (all competitions): WLWWLW
Swansea City Championship form: WLWWDW
Swansea City form (all competitions): LWWDWW
However, the hosts will be without three players due to injury, including fan-favourite Ben Williams.
The Swans will have to continue without Morgan Gibbs-White from now on after the youngster was called back to parent club Wolverhampton Wanderers last week.
Barnsley possible starting lineup:
Walton; Sollbauer, Helik, Andersen; Brittain, Kane, Mowatt, Styles; Adeboyejo, Woodrow, Chaplin
Swansea City possible starting lineup:
Woodman; Cabango, Latibeaudiere, Guehi; Roberts, Smith, Fulton, Grimes, Bidwell; Lowe, Ayew
We say: Barnsley 1-2 Swansea City
Barnsley have a gritty determination about them but even that might not be enough to see them to three points this weekend. Swansea are steeped in Premier League quality, and though Barnsley may well get a goal, the odds are in favour of the visitors, who will want to keep the pressure on Norwich.