As for Villa, they make the trip to Turf Moor sitting in the relegation zone, one point away from safety.
There have been times this season when Villa's performances have suggested that they will not be involved in a relegation scrap come the end of the season, particularly in September and October when they only suffered defeats at Arsenal and Manchester City.
However, losing eight of their last 11 matches in the top flight have resulted in Dean Smith's team dropping into the bottom three, with Watford now only two points adrift in 19th position.
Despite having only recently penned a new contract, Smith is under pressure to keep his job, and there is a feeling that the club's hierarchy would not hesitate to make a change should their Premier League status be put in considerable jeopardy.
With games against Burnley, Brighton & Hove Albion and Watford all to come by January 21, there is an opportunity for Smith to turn things around at a time when he will also likely be provided with funds in the transfer market.
A poor return from those games may prove to be pivotal, however, heaping the pressure on Villa to beginning the New Year with a positive result at Turf Moor.
As for Burnley, Sean Dyche also faces the task of needing to lift his team with four defeats having been recorded from their last half-a-dozen outings.
While those setbacks have come against Manchester City, Tottenham Hotspur, Everton and Manchester United, Dyche needs to ensure that the Clarets do not completely lose their way at this stage of the campaign.
After the meeting with Villa, Burnley face consecutive games with Chelsea, Leicester City, Man United and Arsenal, a run which raises the stakes ahead of their showdown with Villa.
As it stands, just six points separate the two clubs, and victory or defeat could have a decisive bearing on their ambitions for the rest of the season.
Burnley Premier League form: LLWWLL
Aston Villa Premier League form: LLLLWL
Aston Villa form (all competitions): LLWLWL
With Dyche attempting to manage an ongoing groin issue, Ashley Barnes could drop down to the substitutes' bench.
Burnley possible starting lineup:
Pope; Bardsley, Tarkowski, Mee, Pieters; Gudmundsson, Westwood, Cork, McNeil; Rodriguez, Wood
Aston Villa possible starting lineup:
Heaton; Guilbert, Engels, Hause, Taylor; Luiz, Nakamba; El Ghazi, Grealish, Trezeguet; Wesley
We say: Burnley 3-1 Aston Villa
While Villa will feel that they have to right the wrongs of their most recent performances, they do not match up well against Dyche's hard-working side. On that basis, the home side could run out comfortable winners in the North-West.