The Gunners have claimed back-to-back victories over Norwich City and Burnley heading into this battle, with Martin Odegaard netting the winning free kick against the latter.
Mikel Arteta also witnessed his side cruise through to the EFL Cup fourth round with a 3-0 success over AFC Wimbledon on Wednesday night, as Alexandre Lacazette, Emile Smith Rowe and Eddie Nketiah got on the scoresheet.
Here, Sports Mole rounds up all of Arsenal's latest injury and suspension news ahead of the contest.
Status: Minor doubt
Type of injury: Cramp
Possible return date: September 26 (vs. Tottenham)
Kieran Tierney was forced off with cramp against Burnley and was not risked for the EFL Cup win over Wimbledon, but the left-back is expected to be fine for the derby.
ARSENAL'S SUSPENSION LIST
Granit Xhaka returns from a three-game ban this weekend, and Arsenal have no other suspension concerns for the visit of Tottenham.