Ramsey scored the last time Arsenal travelled to Fener in a 5-2 win, and the Welshman is adamant that his side are more than capable of prevailing over the two legs.
He told the club's official website: "It's obviously going to be a very tough game for us but we did a lot of hard work last season to get into this position so we're looking forward to the test of going there.
"We had a really good result there a few years back. The support there is quite phenomenal and I'm sure they'll be up for it again.
"But we realise what we have to do and I'm sure with this group of players, we're more than capable of producing a good performance and result."
The Gunners will travel to Istanbul for the first leg on August 21, with the second leg at the Emirates six days later.