Napoli are third in the Serie A table, one place above Inter, but have a four point lead over them in the standings.
They were knocked out of the Champions League in midweek, despite beating Arsenal 2-0, and will be aiming to get their league form back on track after throwing away a two-goal lead in their 3-3 draw with Udinese last weekend.
Inter are unbeaten in their last eight Serie A fixtures, but have drawn their last three league games to fall 12 points behind leaders Juventus.
Possible starting lineups
Napoli: Rafael, Maggio, Albiol, Britos, Armero, Behrami, Inler, Callejon, Insigne, Mertens, Higuain
Inter : Handanovic, Campagnaro, Rolando, Jesus, Jonathan, Taider, Cambiasso, Alvarez, Nagatomo, Guarin, Palacio
Sports Mole says: 1-1