The Red Devils are still in contention to swoop the FA Cup and the Premier League title following last week's Champions League exit and Sunday's 2-2 draw with Chelsea, which forced through an FA Cup quarter-final replay at Stamford Bridge.
"During a season in England, you know you are going to come under pressure at certain times," the Daily Star quotes Ferdinand as saying.
"It is a gruelling season. We have to be able to deal with that. We have the squad to do it. I am sure the manager (Sir Alex Ferguson) will shake things up."
The North-West outfit are comfortable at the top of the league table with a 12-point lead over rivals Manchester City.