They will be confident of doing so against a struggling Palermo side, who sit outside the relegation zone on goal difference.
A win for Palermo would give them a huge boost in their battle to stay up after a turbulent season both on and off the field. They will be encouraged by their 1-0 victory over Inter Milan last Sunday, which moved them out of the bottom three.
Juventus have won their last seven matches in the league, including last weekend's 2-0 victory over local rivals Torino in the Turin derby.
The win moved them 11 points clear at the top of the Serie A table with 12 left to play for.
Possible starting lineups
Juventus: Buffon; Bonucci, Barzagli, Chiellini; Lichtsteiner, Vidal, Pirlo, Pogba, Asamoah; Marchisio; Vucinic
Palermo: Sorrentino; Von Bergen, Munoz, Dossena, Garcia; Morganella, Donati, Kurtic, Barreto; Miccoli, Boselli
Sports Mole says: 2-0