Antonio Conte's side dominated possession and made the breakthrough early in the second half through Federico Peluso.
Lazio kept going and snatched a vital away goal with just four minutes left when skipper Stefano Mauri tapped home from close range.
Look back on an entertaining match with Sports Mole's minute-by-minute commentary below.
LAZIO: Marchetti, Biava, Cana, Ciani, Cavanda, Gonzalez, Ledesma, Hernanes, Lulic, Mauri, Floccari
He said: "Juventus are the strongest team in the league. But in the last 12 games, we’ve got the most points, we are doing well and we want to do even better."
"Tuesday's encounter and the one in Rome will see a great 180 minutes of football. We have to avoid any lapse in concentration which could cost us dearly."