Jose Mourinho's men lost their opening group encounter against Swiss side Basel, but the six points have seen them move to the top of the standings on goal difference.
On Wednesday they will play host to Schalke at Stamford Bridge, having defeated the German club 3-0 last time out in Gelsenkirchen.
Meanwhile, Julian Draxler should start for the away side. The 20-year-old, who has scored two goals in the competition this season, is believed to have attracted the attention of Manchester United and Arsenal.
Schalke make the trip to West London in positive form away from home, having won six of their last seven matches on the road.
However, Schalke claimed a 2-0 victory from their last trip to London in 2012 at Arsenal's Emirates Stadium.
Possible starting lineups
Chelsea: Cech; Cole, Cahill, Terry, Ivanovic; Essien, Mikel; Schurrle, Oscar, Hazard; Eto'o
Schalke: Hildebrand; Uchida, Howedes, Matip, Aogo; Jones, Boateng, Neustadter, Draxler, Meyer; Szalai
Sports Mole says: 2-0