The Blues take on Bayern Munich at the Allianz Arena on May 19 in the final of Europe's elite competition but find themselves struggling for cover at the back.
However, the Italian remains hopeful that both defenders will be fit enough to marshal the defence this Saturday.
"They are getting better day by day and we are going to try to push them on from tomorrow," Di Matteo told the club's official website.
"We are going to try to push them this week in training and see how far we can take them."
Cahill suffered his injury during Chelsea's semi-final victory over Barcelona.