Millwall vs. Middlesbrough (Wednesday, 3.00pm)
Meanwhile, after back-to-back defeats, Middlesbrough travel to The Den sitting in the relegation zone with just five matches remaining.
We say: Millwall 2-1 Middlesbrough
All things considered, this should be a tense, low-scoring affair. With Millwall having the momentum after their late win at Charlton, we can only back the Lions to edge out their struggling opponents.
West Brom vs. Derby (Wednesday, 5.00pm)
The Baggies have won back-to-back matches and are five points clear of third place, while Derby have been in good form and are within three points of the playoffs.
We say: West Brom 1-1 Derby
Derby are unbeaten in their last three meetings with West Brom, including a 1-1 draw in the reverse fixture 11 months ago. Both teams enter this game on a high and we can see the points being shared.
Birmingham vs. Swansea (Wednesday, 6.00pm)
The Blues have drawn two and lost two since the restart, leaving them down in 17th place, while Swansea are in eighth after a mixed set of results on their return to action.
We say: Birmingham City 0-1 Swansea City
Both teams still have something to play for in the final stretch of the season, with Birmingham looking to make certain of their second-tier status and Swansea chasing down the final playoff spot. Boosted by their return to winning ways last time out, we are backing the Swans to edge Wednesday's clash in the Midlands.
Wigan vs. QPR (Wednesday, 6.00pm)
The Latics were placed in administration last week and are now facing a 12-point deduction, meaning that they are in desperate need of victory against mid-table QPR.
We say: Wigan Athletic 1-0 Queens Park Rangers
Wigan had won three games in a row before losing last time out, while QPR ended a three game losing run with victory in their most recent outing. That makes this one tough to call, though we are tipping the hosts to edge it at the DW Stadium.
Bristol City vs. Hull City (Wednesday, 6.00pm)
The Robins took action after a winless run of nine matches that leaves them nine points off the playoffs, while Hull are also in need of a win to climb clear of the dropzone.
We say: Bristol City 1-0 Hull City
Bristol City are embarking on a new era after parting company with long-serving boss Johnson. We are tipping them to pick up a much-needed victory on Wednesday against a Hull side at serious risk of dropping down a division.
Sheff Weds vs. Preston (Wednesday, 7.45pm)
Alex Neil's side have slipped down to 10th place and are now six points off the playoffs, while Wednesday have lost back-to-back games and are in 15th.
We say: Sheffield Wednesday 1-1 Preston North End
Sheffield Wednesday are winless in four games at home, while Preston North End have not won any of their last four away matches. It all points to a draw at Hillsborough in this clash between two out-of-form sides.