The striker, who scored in the club's FA Cup victory over Arsenal last time out, had been a doubt due to a muscle complaint but takes his place in a side that displays three changes from that match.
Watford: Gomes; Nyom, Britos, Cathcart, Ake; Behrami, Suarez, Capoue; Jurado, Deeney; Ighalo
Subs: Pantilimon, Prodl, Watson, Abdi, Anya, Guedioura, Amrabat
Stoke City: Butland; Bardsley, Cameron, Wollscheid, Muniesa; Whelan, Imbula; Walters, Afellay, Arnautovic; Joselu
Subs: Haugaard, Ireland, Adam, Diouf, Teixeira, Crouch, Krkic