The 28-year-old, who has had a direct hand in more than half of his side's goals in qualifying so far, missed the match with Serbia due to suspension but returns to the fold as Chris Coleman's side welcome Austria to the Principality Stadium.
Wales, who have drawn each of their last five games in Group D, make just two changes from their 1-1 draw with Serbia last time out as the suspended Joe Allen and free agent Joe Ledley drop out to be replaced by Bale and Tom Lawrence.
Aaron Ramsey has overcome a slight calf injury to start the match, which could see Wales close the gap on second-placed Republic of Ireland to two points following their draw with Georgia earlier this afternoon.
Austria also welcome a key player back from suspension as Marko Arnautovic returns, with the West Ham United man having scored twice in the reverse fixture.
Wales: Hennessey; Gunter, Chester, Williams, Richards, Davies; Lawrence, Ramsey, Bale, Edwards; Vokes
Subs: Ward, A Davies, King, Robson-Kanu, Evans, Ampadu, Ledley, Lockyer, Collins, J Williams, Woodburn, Watkins
Austria: Lindner; Prodl, Dragovic, Alaba; Hinteregger, Baumgartlinger, Ilsanker, Lainer, Sabitzer, Harnik, Arnautovic
Subs: Bachmann, Kuster, Grillitsch, Schaub, Hierlander, Bauer, Gregoritsch, Janko, Danso, Laimer, Wober
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