The 27-year-old will deputise in place of AS Roma keeper Maarten Stekelenburg, who suffered a head injury during a match with Inter Milan.
A victory for the Dutch will see them secure top spot in their Euro 2012 qualifying group and Vorm is confident that his teammates will reach their target.
"Against Moldova we just need to make sure we play to our capabilities," Vorm told a press conference.
"If we play like we have done in recent years we will be okay and will top the group.
"We have so much quality. We play a lot of good football and score a lot of goals. We just need to maintain that level."
Vorm joined the Swans from FC Utrecht in the summer.