Having not featured in the top flight since the turn of the year, the hosts sit 10th, albeit with games in hand, while Antonio Conte's men can climb to fifth with a victory, and here Sports Mole rounds up the team news for the two sides.
Out: Daniel Amartey (international duty), Wilfred Ndidi (international duty), Nampalys Mendy (international duty), Kelechi Iheanacho (international duty), Wesley Fofana (broken leg), Jamie Vardy (hamstring), Jonny Evans (thigh), Ricardo Pereira (broken leg), Ryan Bertrand (knee)
Sports Mole's predicted XI: Schmeichel; Albrighton, Soyuncu, Vestergaard, Thomas; Tielemans, Dewsbury-Hall; Lookman, Maddison, Barnes; Daka
Out: Son Heung-min (muscle)
Sports Mole's predicted XI: Lloris; Tanganga, Sanchez, Davies; Royal, Winks, Hojbjerg, Sessegnon; Alli, Kane, Moura