Wednesday won their first game in seven attempts with a 3-0 win over fellow strugglers Ipswich Town on Saturday and will be looking to capitalise on the three points with another victory.
The visitors have been in better form, with all four of their league wins so far all coming in the last six games, most recently a 3-0 victory over Derby County.
Both managers could be reluctant to change winning ways, with Jay Bothroyd likely to continue in attack for Wednesday and the speedy Michail Antonio on the left. Darren Ferguson will be keen for Saido Berahino to add to his two goals against Derby.
Sheffield Wednesday: DLDLW
Wednesday: Kirkland; Buxton, Gardner, Jones, Llera; Corry, Semedo, Barkley, Antonio; O'Grady, Bothroyd
Peterborough: Olejnik; Alcock, Brisley, Little, Ntlhe; Bostwick, McCann, Knight-Percival, Tomlin; Boyd, Berahino
Sports Mole says: 1-1