The Owls are currently in 18th place, but they are only three points above safety, and manager Dave Jones will be aware that they cannot afford to lose at home to the Tractor Boys.
Despite failing to record a victory in their past two matches, Wednesday have been in good form and Jones could select the same starting lineup that started the midweek draw with Blackpool.
Ipswich boss Mick McCarthy has headed something of a revival from the Portman Road outfit in the past two months, and they are five points clear of relegation with three games remaining.
They continued their impressive form in midweek with a comprehensive 3-0 victory over Crystal Palace, and McCarthy could name the same side that started that game.
Sheffield Wednesday: WDWWLD
Ipswich Town: WWDWLW
Possible starting lineups
Sheffield Wednesday: Kirkland; Buxton, Gardner, Llera, Helan; J.Johnson, Pugh, Holden, Prutton, Coke; Howard
Ipswich Town: Loach; Cresswell, Chambers, Stearman, Smith; Edwards, N'daw, Emmanuel-Thomas, Hyam; Murphy, Nouble
Sports Mole says: 1-1