Marcelo and Dani Carvajal drop down to the bench as Danilo and Pepe earn recalls, while it is all change in the middle of the field as Luka Modric, James Rodriguez and Casemiro come in for Isco, Toni Kroos and Mateo Kovacic.
Ronaldo suffered a muscular injury this week so misses the trip to the Ipurua Municipal Stadium while Bale is out for the next two games after seeing red against Las Palmas, so manager Zinedine Zidane names an all-new front three this afternoon.
Meanwhile, Eibar boss Jose Luis Mendilibar makes four changes to the side that claimed a 2-2 draw at Real Sociedad on Tuesday night as the side make an unlikely push for the European places.
Eibar: Yoel; Capa, Ramis, Dos Santos, Luna; Escalante, Garcia, Adrian; Leon, Enrich, Pena
Subs: Riesgo, Galvez, Rivera, Inui, Kike, Arbilla, Bebe
Real Madrid: Navas; Danilo, Ramos, Pepe, Nacho; Modric, Casemiro, James; Lucas, Benzema, Asensio
Subs: Casilla, Carvajal, Kroos, Marcelo, Kovacic, Mariano, Isco
Keep up with all of the action from Spain this afternoon with Sports Mole's live text commentary here.