Real Madrid have announced that they have five new coronavirus cases in their squad, with four players and one staff member returning positive tests.
Los Blancos revealed on Wednesday that both Luka Modric and Marcelo would enter a period of self-isolation, having tested positive for the virus at the club's training ground.
The La Liga leaders have now confirmed that first-team players Marco Asensio, Gareth Bale, Andriy Lunin and Rodrygo have returned positive tests, in addition to assistant coach Davide Ancelotti.
"Real Madrid CF reports that our players Asensio, Bale, Lunin and Rodrygo, and our first technical assistant Davide Ancelotti have tested positive for COVID-19," read a statement on the club's official website.
Los Blancos are due to continue their La Liga campaign against Cadiz on Sunday, but the match could be in doubt if the outbreak worsens.
In addition to the six players who have tested positive for the virus, the league leaders will be without the services of the injured Dani Ceballos for their next contest at the Bernabeu.