Zinedine Zidane was reportedly considering resting a number of his first-team stars for the La Liga clash, but the BBC all start, while Toni Kroos, Luka Modric and Casemiro are all present in midfield.
As for the hosts Barcelona, head coach Ernesto Valverde has preferred Philippe Coutinho to Ousmane Dembele, while Andres Iniesta is fit for his last Clasico despite suggestions that the midfielder could miss out through injury.
Barcelona have already been crowned champions and sit 15 points clear of third-placed Real Madrid, who would move to within one point of second-placed Atletico Madrid with a win.
Barcelona: Ter Stegen; Roberto, Pique, Umtiti, Alba; Rakitic, Busquets, Iniesta; Coutinho, Suarez, Messi
Subs: Cillessen, Paulinho, Dembele, Alcacer, Semedo, D.Suarez, Vermaelen
Real Madrid: Navas; Nacho, Varane, Ramos, Marcelo; Modric, Casemiro, Kroos; Bale, Benzema, Ronaldo
Subs: Casilla, Vallejo, Theo, Lucas, Asensio, Kovacic, Ceballos