The 24-year-old is suffering with a thigh injury, but fellow stopper Robert Green has recovered from an illness and makes the starting XI in between the posts.
Meanwhile, Nedum Onuoha and Sandro will not take part in tonight's game as they are both injured, but Eduardo Vargas is in Harry Redknapp's starting lineup following his brace against Liverpool last week.
Aston Villa defender Philippe Senderos has failed to recover from a thigh injury in time to feature, while Christian Benteke is set to continue in attack after making his first start since March in the 3-0 defeat to Everton.
Queens Park Rangers: Green, Isla, Caulker, Dunne, Suk-Young, Vargas, Sandro, Henry, Fer, Austin, Zamora
Subs: Murphy, Traore, Ferdinand, Hill, Phillips, Kranjcar, Hoilett
Aston Villa: Guzan, Lowton, Vlaar, Clark, Cissokho, Westwood, Cleverley, Sanchez, Weimann, Agbonlahor, Benteke
Subs: Given, Okore, Cole, Bent, Bacuna, Richardson, N'Zogbia
Follow all the action from tonight's game with Sports Mole's live match commentary.