These two clubs head into their encounter at the Estadio do Dragao as joint leaders of Group A following victories on the opening day of the competition last month.
The hosting Portuguese will have Rolando available for selection again after he completed his one-match suspension in European competitions.
Winger Silvestre Varela may also return to the starting lineup following a short spell on the sidelines.
One player that has caused problems to PSG in the past is Lucho Gonzalez, who has scored on two previous occasions against Carlo Ancelotti's side. The Argentine has also scored in eight consecutive Champions League seasons.
Visiting PSG should be able to call upon Ezequiel Lavezzi, who has recovered from a muscular problem.
French international Jeremy Menez may also be recalled to the starting lineup.
Porto: Helton; Lopes, Otamendi, Rolando, Alex Sandro; Defour, Lucho, Moutinho; Varela, Martinez; Rodriguez
PSG: Sirigu; Jallet, Alex, Silva, Maxwell; Chantome, Pastore, Matuidi; Menez, Lavezzi; Ibrahimovic
Sports Mole says: 2-2