The Rosanero have won two of their last three league matches and Dybala believes that they have enough firepower in attack to worry their opponents.
"The Rossoneri are a great side and we will face them with the respect befitting their history," he told Sky Sport Italia. "They play good football, but we can hurt them with the pace of our forwards.
"We will fight like animals, just as our Coach [Giuseppe] Iachini asks, to pick up points."
Palermo are 18th in the Serie A table.