Bottom-place Plymouth shocked Northampton 4-1 at Home Park to give their League Two survival hosts a boost.
Argyle were 4-0 to the good at the break thanks to goals from Simon Walton, Nick Chadwick, Will Atkinson and Ashley Hemmings. Adebayo Akinfenwa scored a late consolation for the visitors.
League leaders Southend could only manage a 1-1 draw at home to Bristol Rovers, while Crawley Town closed moved level on points at the top of the table with a 2-1 win at Rotherham.
Cheltenham picked up a 3-1 win away at Oxford United, with playoff hopefuls Shrewsbury, Burton Albion and Swindon all picking up wins.
At the foot of the table, Dagenham & Redbridge were soundly beaten 3-0 by Accrington Stanley, while Bradford settled for a goalless draw at Gillingham.
Saturday's League Two Results: Accrington 3-0 Dag & Red;
Burton Albion 3-2 AFC Wimbledon; Crewe 1-0 Hereford; Gillingham 0-0 Bradford; Oxford Utd 1-3 Cheltenham; Plymouth 4-1 Northampton; Rotherham 1-2 Crawley Town; Shrewsbury 2-0 Morecambe; Southend 1-1 Bristol Rovers; Swindon 2-0 Aldershot