Cavani will be deployed alongside Lorenzo Insigne as Walter Mazzarri's side will aspire to win their second successive Serie A match.
Marek Hamsik will continue to be the creator-in-chief in attacking midfield for Napoli.
Fiorentina will have Stevan Jovetic pulling the strings for them in Naples tonight, with Mounir El Hamdaoui hoping to be at the end of some quality passes.
Gonzalo starts in central defence for the Viola and David Pizarro will be the enforcer in midfield.
Napoli: De Sanctis, Cannavaro, Britos, Campagnaro, Dzemaili, Behrami, Hamsik, Zuniga, Maggio, Insigne, Cavani
Fiorentina: Viviano, Gonzalo, Tomovic, Roncaglia, Valero, Caldeira, Pizarro, Pasqual, Cuadrado, Jovetic, El Hamdaou