The eighth- and 12th-placed teams, respectively, will be hoping to take advantage of Preston North End's poor form of late and claim a top-six spot for their own.
Millwall have recorded the joint-most draws of any side in the Championship this season with 15 - along with Cardiff City - and their recent form is indicative of that tendency.
In the eight league games they have played since the start of February, half have been stalemates, with just two defeats but only two victories.
Replicating their 1-0 away win over Derby from earlier in the season would be a great way to generate some momentum, particularly given their strong record at The Den.
The reverse fixture was one of just two defeats suffered by Derby at Pride Park in the league this term, and Phillip Cocu's side may not feel confident of returning the favour by winning in London.
The Rams have picked up just 14 points from their 18 league games on the road this term, winning just three times and losing a whopping 10.
Only Charlton Athletic, Luton Town and Barnsley - the three sides in the relegation zone - have worse away records in the division than Cocu's side this season.
Derby are five points off the playoff spots and their inability to recreate their home performances on the road could see the teams ahead of them start to pull away in the hunt for promotion.
Millwall Championship form: DWLDDW
Derby County Championship form: LDDLWW
Derby County form (all competitions): DDLWDW
Millwall manager Rowett is without three players ahead of this fixture.
Mason Bennett will not be eligible to feature as he is on loan from Derby.
Meanwhile, Derby head coach Cocu has the same number of absentees to contend with.
Krystian Bielik, however, is out for the rest of the season with a serious knee injury.
Millwall possible starting lineup:
Bialkowski; Romeo, Hutchinson, Cooper, M. Wallace; J. Wallace, Molumby, Woods, Ferguson; Bradshaw, Smith
Derby County possible starting lineup:
Hamer; Bogle, Wisdom, Clarke, Forsyth; Shinnie, Bird; Waghorn, Sibley, Knight; Martin
We say: Millwall 0-0 Derby County
Derby have won their last two games and two of their last four on the road. Millwall's strength at home, having lost just three games at The Den this term, means the two sides could end up cancelling each other out.