Premier League GW6: Injury news, team news, absentees and doubts for every club

The sixth gameweek of the 2025-26 Premier League campaign will begin on Saturday afternoon, with Manchester United heading to Brentford, as the Red Devils look to build on their win over Chelsea last time out.

Arguably the pick of this weekend's matches comes on Sunday afternoon, as Newcastle United prepare to welcome Arsenal, while the action will conclude on Monday night, with Everton hosting West Ham United.

Here, Sports Mole rounds up all of the injury news, team news, doubts and absentees for every club ahead of the sixth set of fixtures in England's top flight, as the Premier League table starts to take shape.

BRENTFORD VS. MANCHESTER UNITED (Saturday, 12.30pm)

BRENTFORD

Out: Gustavo Nunes (thigh), Paris Maghoma (unspecified)

Doubtful: Reiss Nelson (illness)

MAN UNITED

Out: Lisandro Martinez (knee), Casemiro (suspended), Noussair Mazraoui (unspecified), Amad Diallo (personal)

Doubtful: None

LEEDS UNITED VS. BOURNEMOUTH (Saturday, 3pm)

LEEDS

Out: Lucas Perri (muscle), Wilfried Gnonto (calf)

Doubtful: Daniel James (knock)

BOURNEMOUTH

Out: Enes Unal (knee), Adam Smith (hamstring)

Doubtful: Lewis Cook (shoulder)

CHELSEA VS. BRIGHTON & HOVE ALBION (Saturday, 3pm)

CHELSEA

Out: Mykhaylo Mudryk (suspended), Levi Colwill (knee), Dario Essugo (thigh), Liam Delap (thigh), Robert Sanchez (suspended), Cole Palmer (groin), Tosin Adarabioyo (calf), Wesley Fofana (concussion), Facundo Buonanotte (ineligible)

Doubtful: Marc Guiu (knock), Benoit Badiashile (knock), Romeo Lavia (unspecified)

BRIGHTON

Out: Solly March (knee), Adam Webster (knee), Jack Hinshelwood (ankle)

Doubtful: None

MANCHESTER CITY VS. BURNLEY (Saturday, 3pm)

MAN CITY

Out: Omar Marmoush (knee), Rayan Cherki (thigh), Rayan Ait-Nouri (muscle), Mateo Kovacic (calf), Abdukodir Khusanov (foot)

Doubtful: None

BURNLEY

Out: Zeki Amdouni (knee), Jordan Beyer (knee), Connor Roberts (unspecified), Armando Broja (fitness)

Doubtful: Jacob Bruun Larsen (knock)

CRYSTAL PALACE VS. LIVERPOOL (Saturday, 3pm)

PALACE

Out: Chadi Riad (knee), Cheick Doucoure (knee), Caleb Kporha (back), Walter Benitez (finger)

Doubtful: None

LIVERPOOL

Out: Hugo Ekitike (suspended), Giovanni Leoni (knee)

Doubtful: None

NOTTINGHAM FOREST VS. SUNDERLAND (Saturday, 5.30pm)

FOREST

Out: Nicolas Dominguez (knee), Ola Aina (muscle), Douglas Luiz (hamstring), Murillo (ankle)

Doubtful: None

SUNDERLAND

Out: Leo Hjelde (Achilles), Habib Diarra (groin), Reinildo (suspended), Romaine Mundle (thigh), Dennis Cirkin (wrist), Aji Alese (shoulder), Luke O'Nien (shoulder)

Doubtful: None

TOTTENHAM HOTSPUR VS. WOLVERHAMPTON WANDERERS (Saturday, 8pm)

TOTTENHAM

Out: James Maddison (ACL), Dejan Kulusevski (knee), Radu Dragusin (knee), Kota Takai (ankle), Yves Bissouma (knock)

Doubtful: Dominic Solanke (ankle), Ben Davies (knee), Randal Kolo Muani (thigh), Pape Sarr (thigh)

WOLVES

Out: Leon Chiwone (knee)

Doubtful: Andre (calf)

ASTON VILLA VS. FULHAM (Sunday, 2pm)

ASTON VILLA

Out: Ross Barkley (personal), Youri Tielemans (calf), Amadou Onana (hamstring)

Doubtful: Emiliano Martinez (knock)

FULHAM

Out: None

Doubtful: Kevin (shoulder)

NEWCASTLE UNITED VS. ARSENAL (Sunday, 4.30pm)

NEWCASTLE

Out: Yoane Wissa (knee), Jacob Ramsey (ankle), Fabian Schar (head)

Doubtful: None

ARSENAL

Out: Gabriel Jesus (knee), Kai Havertz (knee), Noni Madueke (knee), Piero Hincapie (groin)

Doubtful: Martin Odegaard (shoulder)

EVERTON VS. WEST HAM UNITED (Monday, 8pm)

EVERTON

Out: Merlin Rohl (groin), Jarrad Branthwaite (hamstring)

Doubtful: None

WEST HAM

Out: Tomas Soucek (suspended), Aaron Wan-Bissaka (stomach)

Doubtful: None

PREMIER LEAGUE GAMEWEEK SIX: TEAM NEWS BY CLUB

ARSENAL (vs. Newcastle)

Out: Gabriel Jesus (knee), Kai Havertz (knee), Noni Madueke (knee), Piero Hincapie (groin)

Doubtful: Martin Odegaard (shoulder)

ASTON VILLA (vs. Fulham)

Out: Ross Barkley (personal), Youri Tielemans (calf), Amadou Onana (hamstring)

Doubtful: Emiliano Martinez (knock)

BOURNEMOUTH (vs. Leeds)

Out: Enes Unal (knee), Adam Smith (hamstring)

Doubtful: Lewis Cook (shoulder)

BRENTFORD (vs. Man United)

Out: Gustavo Nunes (thigh), Paris Maghoma (unspecified)

Doubtful: Reiss Nelson (illness)

BRIGHTON (vs. Chelsea)

Out: Solly March (knee), Adam Webster (knee), Jack Hinshelwood (ankle)

Doubtful: None

BURNLEY (vs. Man City)

Out: Zeki Amdouni (knee), Jordan Beyer (knee), Connor Roberts (unspecified), Armando Broja (fitness)

Doubtful: Jacob Bruun Larsen (knock)

CHELSEA (vs. Brighton)

Doubtful: Marc Guiu (knock), Benoit Badiashile (knock), Romeo Lavia (unspecified)

CRYSTAL PALACE (vs. Liverpool)

Out: Chadi Riad (knee), Cheick Doucoure (knee), Caleb Kporha (back), Walter Benitez (finger)

Doubtful: None

EVERTON (vs. West Ham)

Out: Merlin Rohl (groin), Jarrad Branthwaite (hamstring)

Doubtful: None

FULHAM (vs. Aston Villa)

Out: None

Doubtful: Kevin (shoulder)

LEEDS (vs. Bournemouth)

Out: Lucas Perri (muscle), Wilfried Gnonto (calf)

Doubtful: Daniel James (knock)

LIVERPOOL (vs. Palace)

Out: Hugo Ekitike (suspended), Giovanni Leoni (knee)

Doubtful: None

MANCHESTER CITY (vs. Burnley)

Out: Omar Marmoush (knee), Rayan Cherki (thigh), Rayan Ait-Nouri (muscle), Mateo Kovacic (calf), Abdukodir Khusanov (foot)

Doubtful: None

MANCHESTER UNITED (vs. Brentford)

Out: Lisandro Martinez (knee), Casemiro (suspended), Noussair Mazraoui (unspecified), Amad Diallo (personal)

Doubtful: None

NEWCASTLE UNITED (vs. Arsenal)

Out: Yoane Wissa (knee), Jacob Ramsey (ankle), Fabian Schar (head)

Doubtful: None

NOTTINGHAM FOREST (vs. Sunderland)

Out: Nicolas Dominguez (knee), Ola Aina (muscle), Douglas Luiz (hamstring), Murillo (ankle)

Doubtful: None

SUNDERLAND (vs. Forest)

Out: Leo Hjelde (Achilles), Habib Diarra (groin), Reinildo (suspended), Romaine Mundle (thigh), Dennis Cirkin (wrist), Aji Alese (shoulder), Luke O'Nien (shoulder)

Doubtful: None