Sterling has been absent from a number of matches through injury while Jesus recently returned from a knee problem sustained over Christmas, but the attacking pair both feature in Pep Guardiola's side for the game in the Potteries.
Jese Rodriguez has been brought into the team as his replacement as Stoke look to end a run of five matches without success.
Stoke City: Butland; Bauer, Zouma, Martins Indi, Stafylidis; Ndiaye, Cameron, Allen; Shaqiri, Jese, Choupo-Moting
Subs: Haugaard, Johnson, Shawcross, Adam, Fletcher, Sobhi, Crouch
Manchester City: Ederson; Walker, Kompany, Otamendi, Zinchenko; Fernandinho, D.Silva, De Bruyne, Sterling, Sane; Jesus
Subs: Bravo, Danilo, Stones, Gundogan, Laporte, Bernardo, Yaya Toure
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