The 29-year-old is just two goals short of equalling Man City's all-time goalscoring record, having scored 175 times since moving to the Etihad Stadium in 2011.
Eric Brook is the current record holder at the club with 177 goals, a feat which has not been bettered by any single player since 1939, but Aguero will get his chance to do so against Crystal Palace on Saturday.
Discussing Aguero, Guardiola told Sky Sports News: "All we can say is just to convince him to be involved in the way we want to play - not to be [just] like a striker heading the ball in the box and scoring a goal, but to try to make one high press in the right moment to help to win the ball as quickly possible, to attack as quickly as possible and to be involved in the process to play football.
"I like the strikers who play in the process, like I don't just like the central defenders to defend. They have to be involved in the play. All the players in the world decide to play football for one reason - to play with the ball. Especially when they were kids, they enjoyed the training sessions when they had the ball, and I like all of them to be involved in that. Sergio too.
"But of course he has the character to score goals. He had it in the past in Argentina as a young boy. His mother and father gave him that talent. He will die scoring goals, there is no doubt about that."
Aguero has scored six goals in as many appearances this season, including a hat-trick - his 10th for the club - in last week's 6-0 hammering of Watford.