Dortmund recovered from three consecutive defeats with a 3-1 victory over Napoli in the Champions League but they must start winning again in the league.
Mainz are on a good run of form, which includes three wins from four, but they will still need to be at their best to beat a rejuvenated Dortmund side.
Possible starting lineups
Mainz: Wetklo; Noveski, Pospech, Park, Bell; Zimling, Muller, Geis, Soto; Polter, Okazaki
Dortmund: Weidenfeller; Piszczek, Friedrich, Sokratis, Grosskreutz; Sahin, Bender; Blaszczykowski, Mkhitaryan, Reus; Lewandowski
Sports Mole says: 1-2