The Bianconeri wrapped up the Serie A title last weekend and may have one eye on their Champions League visit to Real Madrid, while their opponents are fighting for survival.
It has been a great week to be a fan of Juventus, with the club enjoying success at home and in Europe, and their hopes of landing a historic treble are still firmly on track.
They have also been able to take their outstanding league form into Europe and they are now just one game away from the Champions League final, after claiming a 2-1 win over holders Real Madrid in the first leg of their semi-final clash on Tuesday evening.
Alvaro Morata gave the Bianconeri an early lead, before Cristiano Ronaldo headed in the equaliser. However, a second-half penalty from Carlos Tevez means that they have a crucial advantage going into next week's return meeting at the Bernabeu.
Due to the magnitude of that tie, Allegri is expected to rest a number of key players this weekend, so the likes of Tevez and Andrea Pirlo will probably begin on the bench. That rotation policy has been evident in recent weeks, but wholesale changes to the starting lineup have contributed to defeats at Parma and Torino.
Recent form in Serie A: WLWLWW
Recent form (all competitions): WDLWWW
Cagliari's hopes of staying in the top flight are hanging by a thread, but if their recent form is anything to go by, then they may just have a chance of staying up.
They looked dead and buried just a couple of weeks ago and a 3-0 defeat at home to Napoli saw them lose for the ninth time in 11 games and led to Zdenek Zeman being sacked for the second time this season.
Former Middlesbrough defender Gianluca Festa was then appointed as their manager and it has signalled a remarkable turn in fortunes. In his first game in charge, the club pulled off a shock 3-1 victory away to Europa League semi-finalists Fiorentina.
The Rossoblu were then narrowly beaten by Chievo, but they bounced back to claim a thumping 4-0 win over Parma on Monday evening to move to within six points of Atalanta, with four games of the season left to play.
Having lost both of their meetings with Atalanta this season, they cannot afford to finish level on points with the Nerazzurri due to Serie A using the head-to-head records between teams to separate them.
It means that Cagliari must pick up at least seven points from their remaining games, but even that may not keep them in the top flight. Few would expect them to earn a result at Juventus, but with home games against Palermo and Udinese to come and a clash with fellow strugglers Cesena, they still have a fighting chance.
Recent form: LLLWLW
Juventus are expected to make a number of changes to their side ahead of the trip to the Bernabeu.
However, Duje Cop should keep his place in the attack, after scoring three goals in his last three games.
Juventus possible starting lineup:
Buffon, Padoin, Bonucci, Chiellini, De Ceglie, Vidal, Marchisio, Sturaro, Pereyra, Matri, Llorente
Cagliari possible starting lineup:
Brkic, Pisano, Ceppitelli, Diakite, Avelar, Ekdal, Crisetig, Donsah, Cossu, Cop, Farias
Head To Head
Juventus made light work of Cagliari when these teams met earlier this season, as they cruised to a 3-1 victory in Sardinia.
The Bianconeri have not tasted defeat in their previous 11 games against the Rossoblu, with nine of those meetings ending in victories.
There is usually plenty of excitement whenever these teams play each other and there have been 19 goals in their last five clashes.
We say: Juventus 2-0 Cagliari
Juventus will be heavy favourites to beat Cagliari and it should be a party atmosphere in Turin after last week's title victory. They may not be at full strength, with such a huge game against Real Madrid looming, but we think that Allegri's side should have enough quality to claim the points.