Meanwhile, their hosts on Tuesday night are without a win in the same number of fixtures, meaning that they are already out of contention for qualification.
Italy have been the frontrunners in this group since matchday one, and it has come as no surprise that they have already wrapped up their spot at next summer's Finals with matches to spare.
While Roberto Mancini has watched his side being forced to work hard in order to overcome Finland and Greece in their last two outings, it was exactly what they needed with their fixtures becoming less competitive going forward.
Mancini and this group of players will no doubt have their eyes on trying to end the qualifying campaign with a 100% record, something which has been rarely achieved in recent years.
Nevertheless, now is the time for Mancini to start handing more international experience to the backup members of the squad, with as many as 13 players in this group having earned 10 caps or fewer.
Given that a 26-man squad was named for this double-header, Mancini is seemingly ready to ring the changes, although that may not aid Liechtenstein's bid to cause a shock in Vaduz.
Being on the receiving end of a 6-0 thrashing in Parma as recently as March will still be fresh in their memory, and it was part of a five-game streak without scoring a goal.
However, the minnows deserve credit for how they have bounced back, with the 1-1 draw in Greece representing one of the most notable results in their history.
Finishing strongly to claim a share of the spoils against Armenia at the weekend also suggests that this group of players are starting to find some form ahead of welcoming one of international football's form team to the Rheinpark Stadion.
Liechtenstein form: LLLLDD
Italy form: WWWWWW
As for Liechtenstein, Yanik Frick will expect to be recalled having come off the bench to score against Armenia at the weekend.
Liechtenstein possible starting lineup: B.Buchel; Malin, Kaufmann, Goppel; Rechsteiner, M.Buchel, Polverino, Meier; Salanovic, Hasler, Frick
Italy possible starting lineup: Meret; D'Ambrosio, Mancini, Romagnoli, Biraghi; Cristante, Tonali, Zaniolo; Bernardeschi, Belotti, El Shaarawy
We say: Liechtenstein 0- 3 Italy
While Liechtenstein have improved as the campaign has progressed, Italy should ease their way to another comfortable win with minimal fuss, regardless of whether Mancini makes multiple alterations.