Hull find themselves back down in the bottom three ahead of the weekend's fixture, while Millwall have seen their playoffs hopes dwindle in the last few weeks.
Hull supporters could have been forgiven for believing that their side's fortunes would change for the better after victory over Middlesbrough, but the Tigers' joy was short-lived and they have now suffered two defeats on the bounce in the second tier.
A fixture with an out-of-sorts Bristol City side provided the prime opportunity for Hull to gather momentum in their attempt to distance themselves from the bottom three, but Bristol City managed to end their nine-game winless streak with a 2-1 win over the Tigers in midweek.
Hull are now in a perilous position near the foot of the table as they lie 22nd on 45 points, although Grant McCann's side are only one point below Charlton Athletic with four games left to play.
The Tigers have endured two completely contrasting halves of the season, having gone from promotion hopefuls before Christmas to relegation candidates only a few months later.
One win from their last 16 in the Championship is most certainly a run of form associated with a relegation-threatened side, and Hull are running out of time to secure their safety in the Championship for the 2020-21 campaign.
Millwall have not exactly hit the ground running since the restart either, and the Lions have all but conceded defeat in their bid to make the top six after picking up just one win since the restart.
Gary Rowett's side fell victim to a 2-0 defeat against a struggling Middlesbrough side in midweek and now lie 11th in the table, five points adrift of the playoff places at this very late stage of the campaign.
No-one is denying that Millwall could very well mount a late charge for the top six but their recent performances have left a lot to be desired, and Rowett's men have only managed to accumulate three wins from their last 14 outings in the second tier.
However, with 46 goals conceded this term, Millwall can boast the best defensive record in the league outside the top six, and the Lions have only shipped one goal on the road in their last six fixtures.
Rowett's side will endeavour to stretch their unbeaten away record to four games at the KCOM Stadium, and Millwall have lost to Hull just once in their last six meetings.
Hull City Championship form: LLDWLL
Millwall Championship form: WLDDWL
Hull's only confirmed absentee is on-loan Liverpool midfielder Herbie Kane, who is not expected to feature before the end of the season with a hamstring issue.
Tom Eaves is also pushing for a start up top having been brought on for the second half on Wednesday.
Hull City possible starting lineup:
Long; Pennington, Burke, Wijs, Elder; Stewart, Honeyman; Wilks, Toral, Scott; Eaves
Millwall possible starting lineup:
Bialkowski; Hutchinson, Pearce, Cooper; Romeo, Molumby, Williams, Ferguson; Thompson, J. Wallace; Bradshaw
We say: Hull City 1-2 Millwall
Hull have been nothing short of abysmal since the turn of the year, and Millwall will feel that this fixture gives them an ideal opportunity to keep the pressure on the teams above them, so we expect the Lions to continue their impressive recent away record with a slender victory at the KCOM Stadium.