The Pitmen have won 10 of their 13 league fixtures this season, while their FA Cup run has seen them defeat AFC Telford United, West Auckland Town and Stamford AFC.
The danger man for the Staffordshire outfit is likely to be midfielder Elliott Durrell, who has already netted 19 goals this season.
Crawley will travel to Keys Park on the back of four successive defeats, and manager Richie Barker will be eager to avoid becoming the victim of a Cup upset.
Barker could include Andy Drury, who made an appearance off the substitutes' bench at Bristol City on Tuesday night.
Hednesford Town: DDWWW
Crawley Town: WLLLL
Possible starting lineups
Hednesford Town: Crane; Disney, Francis, Bailey, Campion; Taylor, Osborne, Thompson-Brown, Durrell; Lennon, Harvey
Crawley Town: Jones; Hurst, Sadler, Walsh, McFadzean; Jones, Adams, Proctor, Simpson, Drury; Sinclair
Sports Mole says: 1-2