In a bid to return to some form of normality during the coronavirus pandemic, authorities have given permission for 1,000 supporters to attend the game in Paris.
However, Les Bleus are facing an opposition who have had their preparations significantly disrupted by two squad members registering a positive test, resulting in all Shakhtar Donetsk players having to withdraw.
Here, Sports Mole predicts which players Didier Deschamps could select for the fixture in the country's capital.
Out: Adrien Rabiot (isolation)
France are unable to call upon the services of Adrien Rabiot, who must spend time in Juventus' bio-secure bubble for the majority of the week.
With Portugal and Croatia to follow in quick succession, Deschamps is not expected to name his first-choice XI for this encounter.
Selection could be based on when players last represented their clubs, with many of the players who played on Sunday likely to be left out of the starting lineup.
Lucas Digne and N'Golo Kante should start in defence and midfield respectively after outings on Saturday, and Anthony Martial's dismissal for Manchester United against Tottenham Hotspur may lead to him being given a run out.