The visit of Mick McCarthy's men is the first time that Derby have played since Saturday night's sacking of Clough that was sparked by defeat to arch rivals Nottingham Forest in the East Midlands derby.
If Wassall guides the Rams to a win, then it will be their first at home at the fifth time of asking this season.
Ipswich are arguably the perfect opposition as they have mustered just two goals on their travels this season and have exactly the same, poor record away from home that Derby do on their own turf (one draw, three losses).
In the same fixture between the two sides last season, Ipswich stole a dramatic victory in the dying moments thanks to Carlos Edwards's long-range effort.
Possible starting lineups
Derby: Grant; Smith, Whitbread, Buxton, Forsyth; Eustace, Bryson, Hughes; Ward, Martin, Russell
Ipswich: Gerken; Chambers, Berra, Smith, Cresswell; Anderson, Skuse, Hyam, Tunnicliffe; Murphy, McGoldrick
Sports Mole says: 0-1