The Blues were beaten in the French capital last week as their chances of progressing in the competition suffered a serious blow.
Chelsea returned to winning ways on Saturday with a 3-0 victory over Stoke City in the Premier League. Meanwhile, PSG travel to London having won their last nine games in a row.
PSG are expected to be without Zlatan Ibrahimovic, who suffered a hamstring problem during last week's first leg.
Possible starting lineups
Chelsea: Cech; Ivanovic, Cahill, Terry, Azpilicueta; Lampard, Luiz; Hazard, Willian, Oscar; Torres
PSG: Sirigu; Jallet, Alex, Silva, Maxwell; Cavani, Verratti, Motta, Matuidi, Lavezzi; Lucas
Sports Mole says: 2-1