The 24-year-old, who was already suffering with a knee problem, was carried off during Chelsea's 5-1 FA Cup semi-final win against Tottenham Hotspur on Sunday, and has now been ruled out of the European tie.
Gary Cahill is expected to partner Blues skipper John Terry at the heart of the defence.
Luiz has made 38 appearances for Chelsea this season.
Restore Data
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Arsenal | 34 | 24 | 5 | 5 | 82 | 26 | 56 | 77 |
| 2 | Manchester CityMan City | 33 | 23 | 7 | 3 | 80 | 32 | 48 | 76 |
| 3 | Liverpool | 34 | 22 | 8 | 4 | 75 | 34 | 41 | 74 |
| 4 | Aston Villa | 34 | 20 | 6 | 8 | 71 | 50 | 21 | 66 |
| 5 | Tottenham HotspurSpurs | 32 | 18 | 6 | 8 | 65 | 49 | 16 | 60 |
| 6 | Manchester UnitedMan Utd | 33 | 16 | 5 | 12 | 51 | 50 | 1 | 53 |
| 7 | Newcastle UnitedNewcastle | 33 | 15 | 5 | 13 | 69 | 54 | 15 | 50 |
| 8 | West Ham UnitedWest Ham | 34 | 13 | 9 | 12 | 54 | 63 | -9 | 48 |
| 9 | Chelsea | 32 | 13 | 8 | 11 | 61 | 57 | 4 | 47 |
| 10 | Bournemouth | 34 | 12 | 9 | 13 | 49 | 60 | -11 | 45 |
| 11 | Brighton & Hove AlbionBrighton | 33 | 11 | 11 | 11 | 52 | 54 | -2 | 44 |
| 12 | Wolverhampton WanderersWolves | 34 | 12 | 7 | 15 | 46 | 54 | -8 | 43 |
| 13 | Fulham | 34 | 12 | 6 | 16 | 50 | 54 | -4 | 42 |
| 14 | Crystal Palace | 34 | 10 | 9 | 15 | 44 | 56 | -12 | 39 |
| 15 | Brentford | 34 | 9 | 8 | 17 | 52 | 59 | -7 | 35 |
| 16 | Everton | 34 | 11 | 8 | 15 | 36 | 48 | -12 | 33 |
| 17 | Nottingham ForestNott'm Forest | 34 | 7 | 9 | 18 | 42 | 60 | -18 | 26 |
| 18 | Luton TownLuton | 34 | 6 | 7 | 21 | 47 | 75 | -28 | 25 |
| 19 | Burnley | 34 | 5 | 8 | 21 | 37 | 69 | -32 | 23 |
| 20 | Sheffield UnitedSheff Utd | 34 | 3 | 7 | 24 | 33 | 92 | -59 | 16 |
| > Premier League Full Table | |||||||||
