Jermaine Beckford could make his league debut for the Trotters, having moved to the club from Leicester City earlier this month.
Meanwhile, the home side will play their first game since the departure of Charlie Austin, who scored 28 goals in 40 appearances for Burnley in the last campaign.
Former Sunderland striker Ryan Noble could fill the gap left by Austin, having joined Burnley on a free transfer earlier this summer.
Burnley: Heaton, Mee, Shackell, Duff, Lafferty, Jones, Stanislas, Marney, Wallace, Ings, Noble
Bolton: Bogdan, Mears, Ream, Knight, Baptiste, Eagles, Pratley, Andrews, Vela, N'Gog, Beckford
Sports Mole says: 2-1 to Bolton