Peru vs. Paraguay (Friday, 10.00pm)
Peru managed to finish second in their group with a win on the final day, while Paraguay finished a commendable campaign in Group A in third place, only falling behind Argentina and Uruguay.
We say: Peru 2-1 Paraguay
In what will certainly be a close encounter between two strong and well-matched sides, we could see this going either way, but narrowly give the edge to Peru on Friday.
Los Incas have recent experience of making it to the final, and that alongside a thriving squad at the peak of their powers could see them outsmart this Paraguay side.
Brazil vs. Chile (Saturday, 1.00am)
The host nation qualified at the top of their group, although they did finish with a disappointing draw against Ecuador, while their opponents managed to finish in fourth spot in group A despite an underwhelming end to their group campaign.
We say: Brazil 2-0 Chile
With expectations as high as ever, the Selecao should be able to negotiate their way through a tricky clash with Chile on Saturday, given their slightly superior quality all over the pitch.
At full strength, their attack should have enough to break down Chile's ageing back line, while they have shown plenty of solidity at the back, shipping just two goals from their four games so far.