The Scottish international signed a four-year deal with Queens Park Rangers on Friday having made more than 100 appearances for the Tangerines.
"To lose him is a big blow to me. I'm not happy and I'm sure the fans aren't," Ince told BBC Sport.
"But Matty had a year left and he wasn't prepared to sign a new contract. When an offer comes in for that type of money, business is business. He's gone and I wish him all the best because he's been fantastic for us."
Blackpool currently sit second in the Championship table.