With El Clasico just around the corner, a win this weekend would help the Catalan side keep Real, who are just a point adrift, behind them.
This match does come just a few days before the second leg of Barcelona's Champions League match against Manchester City, with a place in the quarter-finals of the competition up for grabs, so some players could be rested against a side that have not won in their last seven.
Neymar was suspended for the clash against Rayo, so could come in for the visitors, potentially allowing Luis Suarez or Pedro to be rested, but Jordi Alba and Dani Alves will both miss out after picking up a fifth yellow and a red card respectively at Camp Nou last weekend.
Midfielder Sergio Busquets will miss out though as he continues to battle a knee injury which could keep him out of the clash with Real Madrid later this month.
Meanwhile, Eibar will be hoping to end a run of seven straight defeats in the league, a run which has left them just three points clear of the relegation zone.
Dani Garcia will not be available in midfield as he was sent off late on last time, meaning that he is suspended, while Didac Vila remains a doubt with a muscle strain that has kept him out for the last month.
Eibar will also be without Angel, as he underwent emergency appendix surgery on Saturday after dropping out of the defeat to Levante, ruling him out for the next month.
When Barcelona hosted Eibar earlier in the season, they secured a 3-0 win at Camp Nou.
Form in La Liga: LLLLLL
Form in all competitions: LLLLLL
Possible starting lineup: Jaime, Boveda, Ekiza, Lillo, Navas, Capa, Errasti, Manu, Berjon, Nieto, Lekic
Form in La Liga: WWWLWW
Form in all competitions: WLWWWW
Possible starting lineup: Bravo, Pique, Adriano, Bartra, Mathieu, Rakitic, Iniesta, Mascherano, Pedro, Neymar, Messi
Sports Mole says: 0-3