All in all, it has been a positive start to the season for Atletico. The capital giants won their first three league fixtures against Getafe, Leganes and Eibar to top the table with an 100% record. Simeone's side would have been looking for another win at Real Sociedad last weekend, but the home side recorded a 2-0 success.
The loss at Sociedad was a huge disappointment, and Atletico actually fell two goals behind against Juventus in their Champions League group opener on Wednesday night. The Spanish side showed huge character to respond, though, and ultimately claimed a point as Hector Herrera levelled in the final minute.
Nine points is enough for second spot in La Liga heading into this weekend's fixtures, with Sevilla top of the pile on 10 points. Real Madrid are third with eight, while the champions Barcelona sit fifth having only collected seven points during an underwhelming start to their title defence.
Atletico have lost just one of their last 22 home fixtures, keeping 14 clean sheets in the process. There might have been a huge turnaround over the summer in terms of players, but Simeone's work ethic is still clear to see, and it would not be a surprise to see the capital outfit launch a serious challenge for the title.
The next seven days might reveal an awful lot about the team as they face Celta and Mallorca in quick succession before welcoming Real Madrid to the Wanda Metropolitano for the capital derby next Saturday.
One win, one draw and two defeats - that is how Celta have performed in their opening four matches of the 2019-20 La Liga campaign. A total of four points has left them in 16th position, but they are only three points off fifth-placed Barcelona, suggesting that the league table does not mean too much at this stage.
Celta started their new league season with a 3-1 home defeat to Real Madrid, before recording an impressive 1-0 win over Valencia one week later. Fran Escriba's side then drew 1-1 against Sevilla before suffering a 2-0 loss at home to Granada last weekend.
A return of four points is not exactly terrific, but in Real Madrid, Sevilla and now Atletico, Celta would have arguably faced three of the best four teams in the league in their opening five matches.
There is once again huge pressure on Iago Aspas to score the goals this season; the 32-year-old has been absolutely full of them in recent years but is yet to get off the mark during the 2019-20 campaign.
Celta suffered a 2-0 defeat in the corresponding La Liga clash last season, but the Sky Blues did overcome Simeone's side on home soil in the reverse match. That said, not since June 2007 have the Celts managed to beat Atletico in the Spanish capital.
Atletico Madrid form: WWWLD
Celta Vigo form: LWDDL
It would certainly not be a surprise to see Simeone shuffle his pack following the energy-zapping clash with Juve, meaning that the likes of Vitolo, Angel Correa and Hector Herrera are all pushing for starts.
Celta, meanwhile, are hopeful that Rafinha will be fit to make his second debut for the club against Atletico with the on-loan Barca midfielder battling to overcome a calf problem.
Atletico Madrid possible starting lineup: Oblak; Trippier, Savic, Gimenez, Lodi; Vitolo, Saul, Thomas, Koke; Costa, Felix
Celta Vigo possible starting lineup: Blanco; Mallo, Aidoo, Araujo, Olaza; Denis S, Lobotka, Rafinha, Mendez; Mina, Aspas
We say: Atletico Madrid 2-0 Celta Vigo
Celta have had a free week to prepare for this match, but the same cannot be said for Atletico after their demanding clash with Juve. It is difficult to back against Simeone's side at the Wanda Metropolitano, though, and we are expecting a fairly routine home victory on Saturday night.