Leonardo Jardim's side began the French domestic season slowly, but after putting together a remarkable run of conceding just one goal in 11 games, they have every confidence in ending the campaign in the top four.
After adding their seventh clean sheet in a row against Lille last week, the 2013-14 runners-up are likely to be unchanged, with both Tiemoue Bakayoko and Geoffrey Kondogbia still on the sidelines with thigh problems.
Lyon, who hold a four-point advantage at the top of the standings, travel South with an impressive defensive record of their own after putting together five consecutive shutouts.
Les Gones possess a more formidable record in the final third though, with 10 goals coming in their last three matches on the road.
Form in Ligue 1: WWWDWW
Form in all competitions: WDWWWW
Possible starting lineup: Subasic, Raggi, Echiejile, Fabinho, Wallace, Toulalan, Dirar, Joao Moutinho, Ferreira Carrasco, Bernardo Silva, Berbatov
Form in Ligue 1: WWWWWW
Form in all competitions: WWWWLW
Possible starting lineup: Anthony Lopes, Jallet, Dabo, Bisevac, Umtiti, Gonalons, Ghezzal, Ferri, Fekir , Tolisso, Cornet
Sports Mole says: 1-1