The match will pit two impressive records against each other as Arsenal look to extend a run of 13 games without defeat - including 12 wins - while Liverpool bid to make it 11 games unbeaten at the start of a Premier League campaign for only the second time.
Here, Sports Mole selects a combined XI from both squads, only using players who are available this weekend.
Liverpool dominate the combined XI for this match, particularly in defence where the back five all come from Klopp's side - starting with goalkeeper Alisson Becker chosen ahead of both Bernd Leno and Petr Cech.
With Arsenal suffering a defensive injury crisis ahead of the match, including doubts over Hector Bellerin, the main dilemma is whether to choose Joe Gomez as a right-back or a centre-back, but Klopp has preferred the youngster out wide recently with Dejan Lovren therefore selected ahead of Trent Alexander-Arnold.
The rest of the back four is more straightforward, though, with Virgil van Dijk continuing to have an immeasurable impact on the Liverpool defence and Andrew Robertson establishing himself as one of the best left-backs in the division, despite being rested against Cardiff City last weekend.
Rumoured Liverpool target Aaron Ramsey might usually challenge for a place in the team, but he has been out of favour under Unai Emery in recent weeks. Georginio Wijnaldum is also unfortunate to miss out as Mesut Ozil narrowly earns a place ahead of the Dutchman as Arsenal's first representative in the team.
Liverpool skipper Jordan Henderson is expected to return from a hamstring problem this weekend and so takes his place in the team alongside James Milner, who is also expected to be brought back into the Liverpool XI after being rested against Cardiff.
It could quite easily be an all-Liverpool front three too, but Sadio Mane is the unfortunate one to miss out despite scoring twice last time out. Pierre-Emerick Aubameyang gets the nod on that left wing having scored five goals in his last three league games and a joint-league leading seven this season.
Roberto Firmino has not been in the goals as much as Mane and Mohamed Salah - or indeed Alexandre Lacazette - but his importance to the Liverpool team cannot be overstated, and his recent performances have been instrumental in helping Salah to get back on the goal trail with four in his last three.