The NFC North side have 2012 MVP Adrian Peterson, who has 483 rushing yards and five touchdowns from five matches this season.
The head coach told reporters: "All 11 of them have big roles. You have to be in the right place at the right time.
"If you're not, you could pay for it because obviously [Peterson's] speed factor has been shown with a 78-yarder and a 60-yarder, that type of thing, the nose for the ball and being at the right spot at the right time and coming out of the man in the middle, yeah, very important."
The Giants are without a win in 2013.