The Baggies recorded a resounding 3-0 triumph over Southampton last weekend, and they will be confident of building on that success against the Latics.
Wigan go into the match requiring three points to keep the gap to Aston Villa to a minimum.
Villa are five points clear of the relegation zone, and manager Roberto Martinez will be aware that only a victory will do for his side.
West Bromwich Albion: WDLLDW
Wigan Athletic: WDWLLD
Possible starting lineups
West Bromwich Albion: Foster; Reid, Olsson, Ridgewell, McAuley; Yacob, Morrison, Dorrans, Thomas; Long, Lukaku
Wigan Athletic: Robles; Boyce, Stam, Scharner, McCarthy; Maloney, Gomez, McArthur, Beausejour; Kone, McManaman
Sports Mole says: 2-1