While trailing 2-1, the French international keeper managed to deny Matt Taylor, who had been put through clear on goal for West Ham.
"One guy I want to mention is Hugo. He pulled me out of jail when I played Matt Taylor onside. He's got a real shiner for it as well," he told the club's official website.
"That was massive. It was 2-1 at the time and at 3-1, it's probably game over, certainly in terms of winning.
"It would be hard to come back from there, but Hugo made a tremendous save and he did the same in the first half as well."
Lloris joined Spurs last summer from Lyon.